INC Featured Speakers
Saturday 27 June, 2020
Charlotte Teunissen, PhD, Neurochemistry Lab, Amsterdam, University Medical Centers, Amsterdam, Netherlands
Title: Novel Opportunities for Body Fluid Biomarker Development for Neurological Diseases
10.00 - 10.25 (EDT)
There is a strong potential in the use of body fluid biomarkers for different clinical purposes in neurological diseases. Such biomarkers can aid in diagnosis, prognosis, patient stratification and treatment effect monitoring. This value of biomarkers is exemplified by current use in diagnosis and follow-up of patients. This does for example include the analysis of cerebrospinal fluid (CSF) in Alzheimer´s disease for tau protein and abeta-peptides, the search for aquaporin autoantibodies in neuromyelitis optica. Rapid technological developments offer opportunities to develop novel and specific body fluid biomarkers, even in blood. This is shown by the use of blood neurofilament light chain in a variety of neurological diseases.
Michael P. Collins, MD, Medical College of Wisconsin, Milwaukee, WI, USA
Title: Update on the Nonsystematic Vasculitic Neuropathies
11.15 - 11.40 (EDT)
Biography: Michael P Collins, MD, is a Professor of Neurology and Pathology at the Medical College of Wisconsin (MCW) in Milwaukee, Wisconsin. He completed his neurology training at Wilford Hall Medical Center, San Antonio, Texas in 1990 and his neuromuscular fellowship at The Ohio State University in 1996. At MCW, he is the director of the Muscular Dystrophy Association Clinic and Adult Neuromuscular Pathology Laboratory. Professor Collins’ chief research interest has been the vasculitic neuropathies. He has investigated the histopathological features of vasculitic neuropathies and helped to formulate consensus criteria for the histopathological diagnosis of vasculitic neuropathy.
|He has also studied the clinical, epidemiological, and therapeutic aspects of the vasculitic neuropathies, to include collaborations with experts in systemic vasculitis and serial reviews of the literature. Recently, he has focused attention on the nosology of the nonsystemic vasculitic neuropathies. In 2007-2010, he chaired a Peripheral Nerve Society (PNS)-sponsored international task force that developed guidelines on the classification, diagnosis, and treatment of nonsystemic and other vasculitic neuropathies. Together with Dr Robert Hadden, he chairs the Vasculitic Neuropathy Study Group (VNSG) under the auspices of the Inflammatory Neuropathy Consortium of the PNS. In recent years, the VNSG has expanded its membership and sharpened its focus on establishing a registry of patients with vasculitic neuropathies in collaboration with the United Kingdom and Ireland Vasculitis Rare Diseases Group registry and organizing a multicenter study to develop validated disease-specific outcome measures.|