Saturday Education Course Speakers

Educational Course Speakers
Saturday, 27 June, 2019 


Jérôme Devaux, PhD, Institut de Neurosciences de Montpellier, U1051 INSERM, Montpellier, France 
Title: Inflammatory Neuropathies: From Bench to Bedside 

CNRS staff scientist since 2005, I did my PhD at Aix-Marseille University followed by a post-doctoral fellowship at the University of Pennsylvania. I am interested in understanding the pathogenic mechanisms leading to conduction loss in human demyelinating neuropathies and in understanding the function of axonal voltage-gated potassium channels (Kv). We recently demonstrated that cell adhesion molecules of the nodes of Ranvier, are the targets of autoantibodies in patients suffering from chronic inflammatory demyelinating polyneuropathy. Using animal models, we showed that these antibodies are pathogenic and affect the structure of the node of Ranvier. These proteins now serve as biomarkers for this pathology and help therapeutic choice. In addition, we have demonstrated that Kv channels (Kv7.2/3 and Kv3.1) are localized at nodes, and that human mutation affect their trafficking or function.


 


David Bennett, MD, PhD, University of Oxford, Oxford, United Kingdom
Title: Pathomechanisms of Neuropathic Pain

 


David is Professor of neurology and neurobiology at the University of Oxford, honorary consultant neurologist and head of the Division of Neurology. His sub-specialty interest is peripheral neuropathy and neuropathic pain; he administers the neuropathy and pain channelopathy clinic at Oxford University Hospitals. He completed neurology training in London and moved to Nuffield Department of Clinical Neuroscience, Oxford in 2012. He is currently a senior Wellcome clinical scientist. He was bestowed with the Patrick D Wall medal in pain research by the Royal College of Anaesthetists in 2016. He was appointed Honorary Skou professor, Aarhus University 2019. His research interest is to understand the process of nerve injury and repair and prevent unwanted outcomes such as neuropathic pain. He takes a broad experimental approach to this problem ranging from understanding ion channel biology to clinical trials.

 


Eva Feldman, MD, University of Michigan Department of Neurology, Ann Arbor, MI USA
Title: Mechanisms in Diabetic Neuropathy: An Update 

 

Eva L. Feldman, M.D., Ph.D., is the Russell N. DeJong Professor of Neurology at the University of Michigan (U-M).  A neurologist and neuroscientist, she earned her medical and doctoral degrees at U-M and completed neurology training at Johns Hopkins Hospital. With 30 years of continuous NIH funding, Dr. Feldman has pioneered studies on neurological disorders in metabolic diseases. Her work identified dyslipidemia during obesity and diabetes as a driver of brain and nerve damage in children and adults, influencing new patient care guidelines. She currently leads three multi-institutional NIH grants aimed at understanding how lipids cause nervous system injury, with a focus on neuropathy. At U-M, she directs a research program of 25 scientists, and has trained over 100 fellows. Dr. Feldman served as president of the Peripheral Nerve Society (2007-2009), the American Neurological Association (2011-2013), and is a member of the National Academy of Medicine.Eva L. Feldman, M.D., Ph.D., is the Russell N. DeJong Professor of Neurology at the University of Michigan (U-M).  A neurologist and neuroscientist, she earned her medical and doctoral degrees at U-M and completed neurology training at Johns Hopkins Hospital. With 30 years of continuous NIH funding, Dr. Feldman has pioneered studies on neurological disorders in metabolic diseases. Her work identified dyslipidemia during obesity and diabetes as a driver of brain and nerve damage in children and adults, influencing new patient care guidelines. She currently leads three multi-institutional NIH grants aimed at understanding how lipids cause nervous system injury, with a focus on neuropathy. At U-M, she directs a research program of 25 scientists, and has trained over 100 fellows. Dr. Feldman served as president of the Peripheral Nerve Society (2007-2009), the American Neurological Association (2011-2013), and is a member of the National Academy of Medicine.

 


Mike Shy, MD,  The University of Iowa,  Philadelphia, United States
Title: Established and Emerging Outcome Measures for Hereditary Neuropathy

           

 


 

     

 


 

     

 

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