TNC Featured Speakers

TNC Featured Speakers
24 June, 2019

 


Susanna Park, PhD, The University of Sydney, Sydney, Australia
Title:  The Power of Neurophysiology in Chemotherapy-Induced Peripheral Neuropathy

 

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious consequence of cancer treatment, often resulting in deficits in sensation, function and balance, producing long-lasting disability. Neurophysiological techniques such as nerve conduction studies are the gold standard for clinical diagnosis of peripheral neuropathy. In addition to nerve conduction studies, specialised neurophysiological techniques including nerve excitability studies and small fibre assessments have been utilised to yield insights into CIPN pathophysiology. However, there remains controversy over the utility and benefit of neurophysiological assessments in the clinical oncology setting. To understand the predictive and diagnostic value of neurophysiology in clinical oncology and clinical trial settings, we need to identify how to tailor neurophysiological studies to yield the most information about pathophysiology and symptom progression and examine alignment between neurophysiology and patient symptom report. The development of sensitive quantitative assessment tools will be a necessary step towards the identification of successful neuroprotective strategies for patients with CIPN.

 


Alberto Sobrero, MD, IRCC San Martino, Genova, Italy
Title: Relevance of Peripheral Neuropathy in Cancer Patients Treated with Chemotherapy

           

The relevance of neuropathy in the management of solid Tumors  is marginal with the exception of oxaliplatin related peripheral neuropathy, both in the adjuvant and the advanced setting. This is so for 3 reasons : 1 it’s potential irreversibility 2 it’s prevalence  and 3 the lack of efficacious treatments.


Augusto Caraceni berto Sobrero, MD, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Italy
Title:  Palliative Care in Oncology and Neuropathic Pain

        

Augusto Caraceni is Director of Palliative Care, Pain Therapy and Rehabilitation at the Fondazione IRCCS National Cancer Institute since 2007 Milano Italy President European Association for Palliative Care Research Network (EAPC - RN) and just completed is term (2010 – 2018) as Professor of palliative medicine at the Norwegian University of Science and Technology. He was born in Milan on August, the 8th 1960, and board certified in Clinical Neurophysiology (1988) and in Neurology (1993) at the Università di Pavia. In 1986 he participated with Vittorio Ventafridda, in the WHO program to test and disseminate the WHO ladder for cancer pain relief, attended as Clinical Fellow Palliative care service at the Neurology department of Memorial Sloan-Kettering Cancer Center, in New York in 1994. His research and clinical expertise focuses on opiod pharmacotherapy in cancer pain, cancer pain classification and treatment, advanced cancer complications and palliative care. He has published 196 original articles in peer reviewd journals and authored with Luigi Grassi the monographic book, “Delirium: acute confusional states in palliative medicine”, Oxford University Press 2nd ed 2011.